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KMID : 0364020100430050538
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Korean Journal of Thoracic and Cardiovascular Surgery
2010 Volume.43 No. 5 p.538 ~ p.541
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The Management of Heparin-induced Thrombocytopenia with Thrombosis That Developed after Aortic Dissection Surgery
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Kim Jae-Bum
Park Nam-Hee
Choi Sae-Young
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Abstract
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Heparin-induced thrombocytopenia (HIT) is a clinicopathologic condition and adverse drug reaction caused by immunoglobulin G (IgG) antibodies directed against the heparin-platelet factor 4 complex. HIT with thrombosis (HITT) could lead to limb amputation, stroke, myocardial infarction, and death. We report on the successful management of a HITT patient with argatroban therapy.
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KEYWORD
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Heparin, Thrombocytopenia, Thrombosis
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